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Description

Sleep quality, particularly rapid eye movement (REM) sleep, has been linked to emotion regulation, yet the biological mechanisms underlying these links remain poorly understood. This project examines how genetic variation in the serotonin transporter-linked polymorphic region (5-HTTLPR) influences the relationship between REM sleep and emotion regulation in adolescents and young adults. By utilizing EEG headbands to record sleep physiology we are able to collect information on REM duration, REM latency, and the proportion of the night spent in REM sleep. Genetic analysis on buccal swab samples allows us to classify participants as either having short or long allelic variants for the 5-HTTLPR gene. Along with a task that requires participants to either maintain or reappraise their emotions in response to negative or neutral photos, these factors are analysed to test if variation in the 5-HTTLPR gene moderates the association between sleep quality and emotion regulation.

Publication Date

4-30-2026

Keywords

sleep, genetics, serotonin

The Effects of Genetic Variation on Sleep and Emotional Regulation

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