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Instructor/Advisor

Stephen Theberge

Keywords

Pharmaceuticals, Contamination, Environmental Safety

Abstract

Water samples were collected from sites along the Merrimack and Spicket Rivers for identification and quantification of potential contaminants: pharmaceutical and personal care products (PPCPs). River samples were filtered, concentrated, and analyzed by high performance liquid chromatography-mass spectroscopy (HPLC-MS) in order to identify the PPCPs present in each sample. Some of these PPCPs included progesterone, trimethoprim, melatonin, hydrocortisone, and atorvastatin. Upon identification, samples were spiked with PPCPs of known concentrations and standard addition curves were prepared to determine the concentration of PPCPs from each location. These concentrations were compared with typical values reported in literature to determine the potential environmental concern.

Quantitative Analysis of Pharmaceutical and Personal Care Products (PPCPs) in the Merrimack and Spicket Rivers

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