Download

Download Full Text (770 KB)

Instructor/Advisor

Anastassiia Vertii

Keywords

Macrophage Phagocytosis, Immunstaining, Phagocyte

Abstract

The macrophage is a type of white blood cell called a phagocyte that engulfs foreign substances and particles like, bacteria, dead cells, and debris. It then digests them in a process called Macrophage phagocytosis. This process is key to defending the body against pathogens and regulate the inflammation afterward.

Immunostaining is a technique which uses antibodies to detect specific proteins in cells. This can be used to diagnose health conditions like cancer and other infections. Together, these two methods can be combined to detect the ingested particles inside the macrophage and quantify the phagocytic activity occurring in the cell.

This project aims to explore the combination of these techniques through our findings in the lab and quantify those results in a cohesive presentation as well as explain how these techniques can be used for to better the health of those in need.

Impact of Febrile-Like Stress on Mouse Macrophages

Share

COinS