Title

How to MEK Muscle

Document Type

Article - Open Access

Publication Title

Molecular Cell

Publication Date

8-2001

Abstract/ Summary

Myogenesis is inhibited by receptor activation of Ras through the MEK and ERK kinases, but the underlying mechanism is unclear. In this issue of Molecular Cell, Perry et al. show that activated MEK1 forms an inhibitory complex with myogenic transcription factors in the nucleus.