How to MEK Muscle
Article - Open Access
Myogenesis is inhibited by receptor activation of Ras through the MEK and ERK kinases, but the underlying mechanism is unclear. In this issue of Molecular Cell, Perry et al. show that activated MEK1 forms an inhibitory complex with myogenic transcription factors in the nucleus.
Penn, B. H.,
Berkes, C. A.,
Bergstrom, D. A.,
Tapscott, S. J.
(2001). How to MEK Muscle. Molecular Cell, 8(2), 245-246.
Available at: http://scholarworks.merrimack.edu/bio_facpubs/21