MyoD and the Transcriptional Control of Myogenesis
Article - Merrimack Access Only
Seminars in Cell & Developmental Biology
The basic helix-loop-helix myogenic regulatory factors MyoD, Myf5, myogenin and MRF4 have critical roles in skeletal muscle development. Together with the Mef2 proteins and E proteins, these transcription factors are responsible for coordinating muscle-specific gene expression in the developing embryo. This review highlights recent studies regarding the molecular mechanisms by which the muscle-specific myogenic bHLH proteins interact with other regulatory factors to coordinate gene expression in a controlled and ordered manner.
Berkes, C. A.,
Tapscott, S. J.
(2005). MyoD and the Transcriptional Control of Myogenesis. Seminars in Cell & Developmental Biology, 16(4-5), 585-595.
Available at: http://scholarworks.merrimack.edu/bio_facpubs/18